Hyperthermia – Activating the Immune System and Weakening Cancer Cells with Heat

What is hyperthermia?

Hyperthermia is a medical procedure in which targeted heat is used to weaken cancer cells and activate the immune system. During the treatment, tumor tissue is heated locally or systemically to temperatures of about 39°C (102.2°F). The method is based on the principle of “artificial fever” and has been successfully used for years as a complementary therapy for various types of cancer.

How does hyperthermia work in the body?

The effect is based on several mechanisms:

• Tumor cells are sensitive to heat: Unlike healthy cells, cancer cells are less able to compensate for high temperatures – they die off more quickly or become more vulnerable.
• Improved blood circulation: Heating increases blood flow in the tumor area. This allows medications (e.g., chemotherapeutic agents or immune cells) to reach the site of action more effectively.
• Stimulation of the immune system: Hyperthermia stimulates the production of “heat shock proteins.” These signal to the immune system that something is wrong and make tumor cells visible.

When is hyperthermia used?

Hyperthermia is used as a supplement to conventional cancer therapy – especially in the following situations:

• For solid tumors such as breast cancer, prostate cancer, colorectal cancer, pancreatic cancer, or brain tumors
• When conventional therapies are no longer sufficiently effective or are poorly tolerated
• In the treatment of recurrence, to specifically combat relapses
• As part of individualized immune activation

How is hyperthermia combined at Unifontis?

We do not use hyperthermia in isolation, but as a targeted enhancement within the therapy concept. Common combinations include:

• With autologous vaccines, to make tumor cells visible to the immune system
• With gentle chemotherapy, to increase effectiveness with better tolerability
• With infusion therapies, e.g., with AMT or diflunisal, to further support cell regeneration
• The selection is made individually – based on diagnostics, previous illnesses, and therapy goals.

FAQ – Frequently asked questions about Hyperthermia

Is hyperthermia painful?

No. The treatment is generally well tolerated. You will only feel a pleasant warmth. The temperature is continuously monitored.

How often is hyperthermia performed?

This depends on the course of the disease. Usually, several sessions are carried out at weekly intervals – integrated into a holistic treatment concept.