The goal of systemic hyperthermia is to reproduce the beneficial effects of fever.

Heat (for example generated using ultrasound or electromagnetic waves) warms the tumor tissue, putting it under stress. Tumor cells no longer receive the supplies they need. This supports the effects of chemotherapy and radiotherapy. Rather than targeting the tumor tissue directly, the aim is to slow the natural depletion of chemotherapy and radiotherapy. We also engage partner companies to administer hyperthermia treatment.

Systemic hyperthermia is deliberate heating of the whole body to achieve an elevated core temperature for therapeutic purposes. Other terms used are whole-body hyperthermia, systemic or whole body thermal therapy, and hyperpyrexia. Typically, core body temperatures of 41 - 42 °C are induced for 1-2 h, or alternatively 39-40 °C for 4-8 h. Systemic hyperthermia, by virtue of application to the whole body, aims to alleviate systemic disease conditions, in contrast to local or regional hyperthermia that treats only a specific tissue, limb, or body region.